Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K4 | P45985 | 1/20 | 0.49 |
| ▸ | FYN | P06241 | 2/20 | 0.44 |
| ▸ | PRKCI | P41743 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 2/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | GPR68 | Q15743 | 1/20 | 0.38 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12682536 | 0.81 | RAB9A (0.48) | FYNLRRK2TP53CYP3A4THRB | |
| SCHEMBL3452137 | 0.80 | MAP2K4 (0.51) | MAP2K4FYNPRKCILRRK2HTR7 | |
| SCHEMBL3726097 | 0.80 | ALDH1A1 (0.57) | FYNPRKCILRRK2PI4K2AHTR7 | |
| SCHEMBL29492485 | 0.79 | ALDH1A1 (0.54) | TP53CYP3A4THRBALOX15SMN1; SMN2 | |
| SCHEMBL2968260 | 0.79 | ALDH1A1 (0.54) | TP53CYP3A4THRBALOX15SMN1; SMN2 | |
| SCHEMBL20530624 | 0.78 | MAP2K4 (0.47) | MAP2K4FYNPRKCIMTORLRRK2 | |
| SCHEMBL3789303 | 0.78 | MAOB (0.51) | TP53CYP3A4THRBALOX15SMN1; SMN2 | |
| SCHEMBL27955745 | 0.77 | PI4K2A (0.48) | FYNPRKCIPI4K2AACMSDPRSS1 | |
| SCHEMBL14960038 | 0.77 | PRKCI (0.58) | MAP2K4PRKCIACMSDCHRNB4CHRNA3 | |
| SCHEMBL3790924 | 0.77 | KDM4E (0.46) | FYNPRKCIPI4K2ACYP3A4CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9399654-B2 | Iridium-based complexes for ECL | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2016-07-26 | — | — | US | disclosed |
| US-9399654-B2 | Iridium-based complexes for ECL | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2016-07-26 | — | — | US | disclosed |
| US-20150147750-A1 | NEW IRIDIUM-BASED COMPLEXES FOR ECL | WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER (DE) | 2015-05-28 | — | — | US | disclosed |
| US-20150147750-A1 | NEW IRIDIUM-BASED COMPLEXES FOR ECL | WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER (DE) | 2015-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150147750-A1 | NEW IRIDIUM-BASED COMPLEXES FOR ECL | ALPL, ALDH1A3, SOD3 | MAP2K4 2984/4885FYN 4249/4885PRKCI 3073/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.