SCHEMBL167457

SCHEMBL167457

Cc1ccc(C(=O)O)c(N)n1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRP O00591 4/20 0.55
GABRD O14764 4/20 0.55
GABRA1 P14867 4/20 0.55
GABRB1 P18505 4/20 0.55
GABRG2 P18507 4/20 0.55
GABRB3 P28472 4/20 0.55
GABRA5 P31644 4/20 0.55
GABRA3 P34903 4/20 0.55
GABRA2 P47869 4/20 0.55
GABRB2 P47870 4/20 0.55
GABRA4 P48169 4/20 0.55
GABRE P78334 4/20 0.55
GABRA6 Q16445 4/20 0.55
GABRG1 Q8N1C3 4/20 0.55
GABRG3 Q99928 4/20 0.55
GABRQ Q9UN88 4/20 0.55
NAPRT Q6XQN6 1/20 0.47
ALDH1A1 P00352 3/20 0.42
ACLY P53396 1/20 0.41
CYP1A2 P05177 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14917429 0.83 PARP1 (0.53) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL18840131 0.83 SMN1; SMN2 (0.43) GABRPGABRDGABRA1GABRB1GABRG2
Potassium Ion SCHEMBL20565973 0.80 KDM4E (0.39) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL27970428 0.80 MAPT (0.51) ALDH1A1KMT2AMEN1LMNAMAPT
SCHEMBL28641221 0.79 HDAC1 (0.44) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL29942878 0.79 KDM4E (0.54) ALDH1A1SMN1; SMN2LMNAMAPTKDM4E
SCHEMBL21256547 0.79 PLK1 (0.41) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL1266209 0.79 KDM4E (0.54) ALDH1A1SMN1; SMN2LMNAMAPTKDM4E
SCHEMBL11296731 0.79 GABRP (0.38) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL14370837 0.79 GABRP (0.46) GABRPGABRDGABRA1GABRB1GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 240 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118019451-A Fungicidal compositions comprising fludioxonil 先正达农作物保护股份公司 2024-05-10 CN claimed
CN-115209736-A Fungicidal compositions 先正达农作物保护股份公司 2022-10-18 CN claimed
CN-115209735-A Fungicidal compositions 先正达农作物保护股份公司 2022-10-18 CN claimed
EP-3162796-B1 METHOD FOR PRODUCING 2-AMINO-6-METHYLNICOTINIC ACID AGRO KANESHO CO LTD (JP) 2021-06-09 EP claimed
CN-106458908-B The manufacturing method of 2- amino -6- methylnicotinic acids 阿格罗-金正株式会社 2018-11-06 CN claimed
US-9902697-B2 Method for producing 2-amino-6-methylnicotinic acid AGRO-KANESHO CO., LTD. (JP) 2018-02-27 US claimed
US-9714223-B2 2017-07-25 US claimed
US-20170129858-A1 METHOD FOR PRODUCING 2-AMINO-6-METHYLNICOTINIC ACID AGRO-KANESHO CO., LTD. (JP) 2017-05-11 US claimed
EP-3162796-A1 METHOD FOR PRODUCING 2-AMINO-6-METHYLNICOTINIC ACID Agro-Kanesho Co., Ltd. (JP) 2017-05-03 EP claimed
CN-106458908-A Method for producing 2-amino-6-methylnicotinic acid 阿格罗-金正株式会社 2017-02-22 CN claimed
CN-119841817-B Aromatic ester compound containing benzo five-membered ring, and preparation method and application thereof 山东省联合农药工业有限公司 2026-05-12 CN disclosed
EP-4737449-A1 P53-Y220C SELECTIVE SMALL-MOLECULAR REACTIVATOR COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF Changchun Genescience Pharmaceutical Co., Ltd. (CN) 2026-05-06 EP disclosed
US-20250382288-A1 8-AZA QUINAZOLINES AS BRAIN-PENETRANT SOS1-INHIBITORS BOEHRINGER INGELHEIM INT (DE) 2025-12-18 US disclosed
US-20250235543-A1 MODIFIED PROTEINS AND PROTEIN DEGRADERS CULLGEN (SHANGHAI), INC. (CN) 2025-07-24 US disclosed
EP-4587014-A2 C5AR1 ANTAGONISTS AND USES THEREOF Vanqua Bio, Inc. (US) 2025-07-23 EP disclosed
US-4120962-A Fused pyrimidin-4(3H)-ones as antiallergy agents PFIZER INC. (US) 1978-10-17 US disclosed
US-4044134-A FUSED WITH QUINOLINE OR PYRIDINE, 2-METHYL, ETHYL, OR ACETYL GROUP PFIZER INC. (US) 1977-08-23 US disclosed
US-3974161-A Fused pyrimidin-4(3H)-ones as antiallergy agents PFIZER INC. (US) 1976-08-10 US disclosed
US-3962264-A AMMONIA, TETRA-ALKOXY-PROPANE, MALONONITRILE PFIZER INC. (US) 1976-06-08 US disclosed
US-3950160-A INHIBITING THE GROWTH OF WEEDS WITH 2-SUBSTITUTED PYRDIDOPYIMIDINES AND SALTS THEREOF PFIZER INC. (US) 1976-04-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250382288-A1 8-AZA QUINAZOLINES AS BRAIN-PENETRANT SOS1-INHIBITORS SOS1, SOS2, SOST GABRP 3559/4885GABRD 3250/4885GABRA1 1692/4885
US-20170129858-A1 METHOD FOR PRODUCING 2-AMINO-6-METHYLNICOTINIC ACID MAT2A, AADAT, AMPD2 GABRP 2406/4885GABRD 2655/4885GABRA1 1473/4885
US-20250235543-A1 MODIFIED PROTEINS AND PROTEIN DEGRADERS DDB1, DCLRE1A, TP53BP1 GABRP 3529/4885GABRD 2461/4885GABRA1 3175/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.