Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9915520 | 0.83 | NR1H4 (0.45) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL16747360 | 0.79 | MEN1 (0.41) | MAPTSMN1; SMN2LMNAMEN1HTT | |
| SCHEMBL9915484 | 0.78 | MAPT (0.49) | MAPTSMN1; SMN2LMNAMEN1HTT | |
| SCHEMBL9915523 | 0.77 | C5AR1 (0.39) | MAPTSMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL9915434 | 0.74 | NR1H4 (0.44) | SMN1; SMN2LMNATP53 | |
| SCHEMBL9915325 | 0.74 | SMN1; SMN2 (0.43) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL11362734 | 0.73 | KDM4E (0.59) | MAPTSMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL9915302 | 0.73 | TP53 (0.40) | ALDH1A1TP53 | |
| SCHEMBL16747452 | 0.72 | PTPRC (0.36) | MAPTPOLB | |
| SCHEMBL16744418 | 0.71 | MEN1 (0.47) | MAPTSMN1; SMN2LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150148326-A1 | Monobactams | PFIZER (US) | 2015-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150148326-A1 | Monobactams | MGAM, MGAM2, BPGM | MAPT 3674/4885SMN1; SMN2 4574/4885LMNA 4489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.