Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 9/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9915323 | 0.82 | NR1H4 (0.41) | C5AR1MEN1KMT2ACNR1CNR2 | |
| SCHEMBL9915331 | 0.81 | MEN1 (0.40) | MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9915520 | 0.81 | NR1H4 (0.45) | MAPTMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL14124973 | 0.80 | PPIA (0.48) | MAPTMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL16744418 | 0.79 | MEN1 (0.47) | MAPTMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL9915333 | 0.78 | PTPRC (0.40) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL16747359 | 0.77 | MAPT (0.44) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL14124972 | 0.76 | KMT2A (0.45) | MAPTMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL16747360 | 0.75 | MEN1 (0.41) | MAPTMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL9915381 | 0.72 | NPC1 (0.38) | C5AR1MEN1KMT2AKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012073138-A1 | MONOBACTAMS | PFIZER INC. (US) | 2012-06-07 | — | — | WO | disclosed |