Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | STAT3 | P40763 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9915520 | 0.87 | NR1H4 (0.45) | MEN1KMT2ARAB9ANPC1CASP1 | |
| SCHEMBL14124972 | 0.82 | KMT2A (0.45) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL16747452 | 0.80 | PTPRC (0.36) | MAPTKDM4E | |
| SCHEMBL16747359 | 0.79 | MAPT (0.44) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL9915325 | 0.78 | SMN1; SMN2 (0.43) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9915519 | 0.78 | MEN1 (0.44) | MEN1KMT2ARAB9ANPC1CASP1 | |
| SCHEMBL9915523 | 0.75 | C5AR1 (0.39) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL9915333 | 0.74 | PTPRC (0.40) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL9915434 | 0.74 | NR1H4 (0.44) | SMN1; SMN2TP53LMNA | |
| SCHEMBL16747451 | 0.73 | ALDH1A1 (0.40) | MEN1KMT2AALDH1A1TP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150148326-A1 | Monobactams | PFIZER (US) | 2015-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150148326-A1 | Monobactams | MGAM, MGAM2, BPGM | MEN1 2023/4885KMT2A 608/4885RAB9A 2614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.