Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 8/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | VDR | P11473 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9915331 | 0.88 | MEN1 (0.40) | ALDH1A1LMNAEGLN1NPSR1TSHR | |
| SCHEMBL16747452 | 0.87 | PTPRC (0.36) | MMP1 | |
| SCHEMBL9915302 | 0.84 | TP53 (0.40) | ALDH1A1TP53TSHR | |
| SCHEMBL9915434 | 0.82 | NR1H4 (0.44) | LMNATP53TSHR | |
| SCHEMBL9915325 | 0.80 | SMN1; SMN2 (0.43) | ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL9915520 | 0.79 | NR1H4 (0.45) | LMNATP53TSHRMEN1KMT2A | |
| SCHEMBL9915333 | 0.78 | PTPRC (0.40) | NPSR1MEN1KMT2A | |
| SCHEMBL16744416 | 0.76 | EGLN1 (0.42) | EGLN1 | |
| SCHEMBL15279057 | 0.74 | TP53 (0.33) | ALDH1A1LMNAEGLN1NPSR1TP53 | |
| SCHEMBL16747360 | 0.73 | MEN1 (0.41) | ALDH1A1LMNATP53MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150148326-A1 | Monobactams | PFIZER (US) | 2015-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150148326-A1 | Monobactams | MGAM, MGAM2, BPGM | ALDH1A1 1829/4885LMNA 4489/4885EGLN1 3261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.