Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9915381 | 0.87 | NPC1 (0.38) | L3MBTL1CYP3A4LMNAALDH1A1HTT | |
| SCHEMBL22022461 | 0.79 | EGFR (0.41) | LMNAMTNR1A | |
| SCHEMBL9915331 | 0.78 | MEN1 (0.40) | LMNAALDH1A1NPSR1TSHRMEN1 | |
| SCHEMBL28954527 | 0.77 | EPHX2 (0.52) | EPHX2CNR2MTNR1AMEN1KMT2A | |
| SCHEMBL28416107 | 0.76 | EPHX2 (0.54) | CYP2C19EPHX2CYP3A4CNR2ALDH1A1 | |
| SCHEMBL15279057 | 0.75 | TP53 (0.33) | L3MBTL1LMNAALDH1A1HTTNPSR1 | |
| SCHEMBL14136527 | 0.75 | PPARD (0.43) | CYP2C19LMNATSHR | |
| SCHEMBL9915436 | 0.74 | FAAH (0.36) | ALDH1A1TSHR | |
| SCHEMBL16748752 | 0.73 | TP53 (0.34) | CYP2C19L3MBTL1CNR2ALDH1A1HTT | |
| SCHEMBL9915493 | 0.73 | SMN1; SMN2 (0.43) | CYP2C19LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150148326-A1 | Monobactams | PFIZER (US) | 2015-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150148326-A1 | Monobactams | MGAM, MGAM2, BPGM | CYP2C19 714/4885L3MBTL1 1495/4885EPHX2 2417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.