Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16748757 | 0.88 | S1PR2 (0.33) | TP53GAATSHRHTTTDP1 | |
| SCHEMBL9915355 | 0.85 | COMT (0.38) | TP53GAATDP1ALDH1A1L3MBTL1 | |
| SCHEMBL15279057 | 0.84 | TP53 (0.33) | TP53GAATSHRHTTTDP1 | |
| SCHEMBL9915322 | 0.82 | CYP1A2 (0.34) | TP53GAATSHRHTTTDP1 | |
| SCHEMBL9915436 | 0.80 | FAAH (0.36) | TSHRALDH1A1MAPK1 | |
| SCHEMBL9915493 | 0.80 | SMN1; SMN2 (0.43) | HPGDCASP1HSD17B10SMPD1KMT2A | |
| SCHEMBL14136527 | 0.80 | PPARD (0.43) | TP53TSHRHPGDHSD17B10MAPT | |
| SCHEMBL14136603 | 0.80 | USP2 (0.45) | MAPK1 | |
| SCHEMBL14136604 | 0.80 | USP2 (0.45) | GAAHPGDMAPK1SMPD1MAPT | |
| SCHEMBL16748764 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2646436-B1 | MONOBACTAMS | PFIZER (US) | 2015-05-27 | — | — | EP | disclosed |