Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 9/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 9/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 9/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 9/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16748752 | 0.88 | TP53 (0.34) | TDP1GAAMEN1NPC1ALDH1A1 | |
| SCHEMBL9915322 | 0.83 | CYP1A2 (0.34) | TDP1GAAMEN1NPC1ALDH1A1 | |
| SCHEMBL9915355 | 0.83 | COMT (0.38) | TDP1GAAMEN1NPC1ALDH1A1 | |
| SCHEMBL15279057 | 0.83 | TP53 (0.33) | S1PR3TDP1GAAMEN1ALDH1A1 | |
| SCHEMBL14136527 | 0.78 | PPARD (0.43) | MAPTTP53TSHR | |
| SCHEMBL9915493 | 0.78 | SMN1; SMN2 (0.43) | MEN1NPC1MAPTRAB9AKMT2A | |
| SCHEMBL9915356 | 0.78 | MEN1 (0.33) | S1PR3GAAMEN1NPC1ALDH1A1 | |
| SCHEMBL9915436 | 0.77 | FAAH (0.36) | ALDH1A1TSHR | |
| SCHEMBL14136603 | 0.76 | USP2 (0.45) | — | |
| SCHEMBL14136604 | 0.76 | USP2 (0.45) | GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2646436-B1 | MONOBACTAMS | PFIZER (US) | 2015-05-27 | — | — | EP | disclosed |