SCHEMBL167518

SCHEMBL167518

C=Cc1ccccc1CF

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
TSHR P16473 1/20 0.35
NFE2L2 Q16236 1/20 0.32
MEN1 O00255 1/20 0.31
LMNA P02545 1/20 0.31
THRB P10828 1/20 0.31
BLM P54132 1/20 0.31
KMT2A Q03164 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30548396 1.00 ALDH1A1 (0.44) ALDH1A1TSHRNFE2L2MEN1LMNA
SCHEMBL595200 0.80 ALDH1A1 (0.48) ALDH1A1TSHRMEN1LMNATHRB
SCHEMBL29377653 0.80 ALDH1A1 (0.48) ALDH1A1TSHRMEN1LMNATHRB
SCHEMBL50299 0.80 ALDH1A1 (0.48) ALDH1A1TSHRMEN1LMNATHRB
SCHEMBL5072509 0.78 ALDH1A1 (0.46) ALDH1A1TSHRMEN1LMNATHRB
SCHEMBL304527 0.78 ALDH1A1 (0.46) ALDH1A1TSHRMEN1LMNATHRB
SCHEMBL4722670 0.77 NFE2L2 (0.34) NFE2L2
SCHEMBL7030822 0.76 ALDH1A1 (0.44) ALDH1A1TSHRMEN1LMNATHRB
SCHEMBL8892647 0.76 NFE2L2 (0.32) NFE2L2MEN1LMNATHRBBLM
SCHEMBL809312 0.76 ALDH1A1 (0.44) ALDH1A1TSHRMEN1LMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 369 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10858455-B2 Process for the production of water and solvent-free nitrile rubbers ARLANXEO DEUTSCHLAND GMBH (DE) 2020-12-08 US claimed
CN-108126749-B Porous alkaline supported ionic liquid catalyst and preparation method and application thereof 中国科学院过程工程研究所 2020-10-02 CN claimed
US-20160369014-A1 PROCESS FOR THE PRODUCTION OF WATER AND SOLVENT-FREE NITRILE RUBBERS ARLANXEO DEUTSCHLAND GMBH (DE) 2016-12-22 US claimed
EP-2478021-B1 Nitrile rubbers and production of same in organic solvents LANXESS DEUTSCHLAND GMBH (DE) 2015-11-04 EP claimed
US-9023914-B2 Nitrile rubbers and production thereof in organic solvents LANXESS DEUTSCHLAND GMBH (DE) 2015-05-05 US claimed
EP-2641909-A1 Transition metal P-N complexes as polymerization catalysts LANXESS Deutschland GmbH (DE) 2013-09-25 EP claimed
US-20120283351-A1 NITRILE RUBBERS AND PRODUCTION THEREOF IN ORGANIC SOLVENTS LANXESS DEUTSCHLAND GMBH (DE) 2012-11-08 US claimed
EP-2385074-A1 Nitrile rubbers and production of same in organic solvents LANXESS Deutschland GmbH (DE) 2011-11-09 EP claimed
US-8038675-B2 Apparatus for arrhythmia treatment based on spectral mapping during sinus rhythm ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. (US) 2011-10-18 US claimed
EP-2298824-A1 Nitrile rubbers and production of same in organic solvents LANXESS Deutschland GmbH (DE) 2011-03-23 EP claimed
EP-1311612-B1 REACTOR ALLOY OF SYNDIOTACTIC POLYSTYRENE HAVING HIGH IMPACT RESISTANCE SAMSUNG ATOFINA CO LTD (KR) 2007-02-28 EP claimed
EP-1311612-A4 REACTOR ALLOY OF SYNDIOTACTIC POLYSTYRENE HAVING HIGH IMPACT RESISTANCE SAMSUNG ATOFINA CO LTD (KR) 2005-04-06 EP claimed
US-6780938-B2 IN COMPARISON WITH A MELT BLEND WITHOUT IMPAIRING HEAT RESISTANCE AND ELASTIC MODULUS BY INTRODUCING RUBBERY ELASTOMER AND POLYPHENYLENE ETHER SAMSUNG ATOFINA CO. LTD. (KR) 2004-08-24 US claimed
US-20030176581-A1 Reactor alloy of syndiotactic polystyrene having high impact resistance SAMSUNG ATOFINA GMBH & CO. LTD. (KR) 2003-09-18 US claimed
EP-1311612-A1 REACTOR ALLOY OF SYNDIOTACTIC POLYSTYRENE HAVING HIGH IMPACT RESISTANCE Samsung General Chemicals Co., Ltd. (KR) 2003-05-21 EP claimed
WO-2002014425-A1 REACTOR ALLOY OF SYNDIOTACTIC POLYSTYRENE HAVING HIGH IMPACT RESISTANCE SAMSUNG GENERAL CHEMICALS CO., LTD. (KR) 2002-02-21 WO claimed
EP-4697955-A1 AIR FILTER WITH ABLATIVE AND SACRIFICIAL POLYMERS Industrial Polymers and Chemicals, Inc. (US) 2026-02-25 EP disclosed
US-12540270-B2 Polymers and nanoparticles for flooding SAUDI ARABIAN OIL COMPANY (SA) 2026-02-03 US disclosed
US-4098829-A POLYMERIC HYDROQUINONE ANTIOXIDANT DYNAPOL (US) 1978-07-04 US disclosed
US-4054676-A Edible with polymeric hydroquinone antioxidant DYNAPOL (US) 1977-10-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12540270-B2 Polymers and nanoparticles for flooding AQP3, FLNA, AQP4 ALDH1A1 4092/4885TSHR 1499/4885NFE2L2 2149/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.