Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1509679 | 0.76 | GABRA1 (0.41) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL1377895 | 0.76 | MEN1 (0.31) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL30548396 | 0.76 | ALDH1A1 (0.44) | NFE2L2MEN1LMNATHRBBLM | |
| SCHEMBL167518 | 0.76 | ALDH1A1 (0.44) | NFE2L2MEN1LMNATHRBBLM | |
| SCHEMBL2680152 | 0.76 | LMNA (0.55) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL27524455 | 0.76 | PNMT (0.44) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL8863217 | 0.76 | ALDH1A1 (0.38) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL11371115 | 0.73 | MITF (0.40) | MITF | |
| SCHEMBL7125533 | 0.73 | GABRA1 (0.44) | MEN1LMNAKMT2A | |
| SCHEMBL2335217 | 0.73 | CALM1 (0.46) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618792-A | USEFUL FOR TREATING ACUTE RESPIRATORY DISEASES, AND MYOCARDIAL ISHCEMIA-REPERFUSION INJURY | CORTECH, INC. (US) | 1997-04-08 | — | — | US | disclosed |