Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.37 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.36 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.34 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4495601 | 0.83 | ALDH1A1 (0.60) | ALDH1A1MAPK1HTTSMN1; SMN2EPHX2 | |
| SCHEMBL15297183 | 0.76 | HPGD (0.51) | ALDH1A1SMN1; SMN2HPGDNAMPT | |
| SCHEMBL17208800 | 0.74 | HPGD (0.65) | ALDH1A1HTTSMN1; SMN2EPHX2NR1H4 | |
| SCHEMBL7724232 | 0.74 | PRMT1 (0.45) | ALDH1A1MAPK1HTTSMN1; SMN2SETD7 | |
| SCHEMBL19486225 | 0.72 | ALDH1A1 (0.55) | ALDH1A1MAPK1HTTSMN1; SMN2ESR1 | |
| SCHEMBL19489497 | 0.72 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2ESR1MAPTGLA | |
| SCHEMBL16360747 | 0.72 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2ESR1MAPT | |
| SCHEMBL3694813 | 0.71 | CYP2A6 (0.44) | ALDH1A1MAPK1CYP2A6CYP2A13ALDH3A1 | |
| SCHEMBL17967822 | 0.71 | CASP2 (0.58) | ALDH1A1LMNATSHRCYP2C19 | |
| SCHEMBL6205353 | 0.70 | MCHR1 (0.45) | ALDH1A1SMN1; SMN2CYP2A6CYP2A13EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150150893-A1 | ANDROGRAPHOLIDE ANALOGS AND THEIR USE FOR MEDICATION | LIAONING LIFENG SCIENT & TECHNOLOGY DEV COMPANY LTD (CN) | 2015-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150150893-A1 | ANDROGRAPHOLIDE ANALOGS AND THEIR USE FOR MEDICATION | CYP11B1, CYP51A1, CYP11B2 | ALDH1A1 577/4885MAPK1 1370/4885HTT 2872/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.