Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 15/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5134830 | 0.82 | KDM4E (0.40) | ELANE | |
| SCHEMBL2289363 | 0.80 | ELANE (0.42) | ELANE | |
| SCHEMBL3276266 | 0.79 | ELANE (0.42) | ELANE | |
| SCHEMBL8662040 | 0.79 | ELANE (0.40) | ELANE | |
| SCHEMBL387694 | 0.78 | TACR1 (0.40) | MEN1KMT2AELANE | |
| SCHEMBL5487413 | 0.77 | ELANE (0.38) | ELANE | |
| SCHEMBL228960 | 0.77 | ELANE (0.38) | ELANE | |
| SCHEMBL3325560 | 0.76 | TACR1 (0.43) | — | |
| SCHEMBL847832 | 0.75 | CMA1 (0.49) | — | |
| SCHEMBL5494650 | 0.74 | ELANE (0.40) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110092413-A1 | Albumin-Fused Kunitz Domain Peptides | NOVOZYMES BIOPHARMA DK A/S (DK) | 2011-04-21 | — | — | US | disclosed |
| EP-2090589-A1 | Albumin-fused Kunitz domain peptides | Dyax Corp. (US) | 2009-08-19 | — | — | EP | disclosed |
| US-20080274969-A1 | Albumin-Fused Kunitz Domain Peptides | NOVOZYMES DELTA LIMITED (GB) | 2008-11-06 | — | — | US | disclosed |
| EP-1572930-A4 | ALBUMIN-FUSED KUNITZ DOMAIN PEPTIDES | NOVOZYMES DELTA LTD (GB) | 2008-07-09 | — | — | EP | disclosed |
| US-6989369-B2 | Kunitz domain peptides | DYAX CORP. (US) | 2006-01-24 | — | — | US | disclosed |
| US-20050222023-A1 | Albumin-fused kunitz domain peptides | NOVOZYMES BIOPHARMA DK A/S (DK) | 2005-10-06 | — | — | US | disclosed |
| EP-1572930-A2 | ALBUMIN-FUSED KUNITZ DOMAIN PEPTIDES | Delta Biotechnology Limited (GB) | 2005-09-14 | — | — | EP | disclosed |
| US-20040171794-A1 | Kunitz domain peptides | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-09-02 | — | — | US | disclosed |
| WO-2003066824-A2 | ALBUMIN-FUSED KUNITZ DOMAIN PEPTIDES | AVENTIS BEHRING GMBH (DE) | 2003-08-14 | — | — | WO | disclosed |