Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 9/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.36 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16760327 | 0.90 | P2RX7 (0.40) | P2RX7TP53PTGESLMNAGAA | |
| SCHEMBL17917776 | 0.90 | P2RX7 (0.39) | P2RX7TP53PTGESLMNAGAA | |
| SCHEMBL18512984 | 0.88 | HDAC6 (0.41) | P2RX7SCN9A | |
| SCHEMBL16760312 | 0.86 | TP53 (0.41) | P2RX7TP53PTGESLMNAGAA | |
| SCHEMBL17917768 | 0.83 | P2RX7 (0.39) | P2RX7TP53PTGESLMNAGAA | |
| SCHEMBL18503614 | 0.83 | LMNA (0.41) | TP53PTGESLMNAGAAKCNK3 | |
| SCHEMBL16771888 | 0.82 | P2RX7 (0.49) | P2RX7TP53 | |
| SCHEMBL18503619 | 0.82 | TP53 (0.45) | TP53PTGESLMNAGAAKCNK3 | |
| SCHEMBL18503594 | 0.82 | KIF11 (0.41) | P2RX7TP53PTGESLMNAGAA | |
| SCHEMBL16211782 | 0.81 | KDM4E (0.50) | P2RX7TP53PTGESLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170044104-A1 | NEW PESTICIDAL COMPOUNDS AND USES | BAYER ANIMAL HEALTH GMBH (DE) | 2017-02-16 | — | — | US | disclosed |
| US-20170044104-A1 | NEW PESTICIDAL COMPOUNDS AND USES | BAYER ANIMAL HEALTH GMBH (DE) | 2017-02-16 | — | — | US | disclosed |
| US-20170044104-A1 | NEW PESTICIDAL COMPOUNDS AND USES | BAYER ANIMAL HEALTH GMBH (DE) | 2017-02-16 | — | — | US | disclosed |
| EP-3073827-A1 | NEW PESTICIDAL COMPOUNDS AND USES | Bayer Animal Health GmbH (DE) | 2016-10-05 | — | — | EP | disclosed |
| WO-2015078800-A1 | NEW PESTICIDAL COMPOUNDS AND USES | BAYER CROPSCIENCE AG (DE) | 2015-06-04 | — | — | WO | disclosed |
| WO-2015078800-A1 | NEW PESTICIDAL COMPOUNDS AND USES | BAYER CROPSCIENCE AG (DE) | 2015-06-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170044104-A1 | NEW PESTICIDAL COMPOUNDS AND USES | ACHE, DDT, DNPH1 | P2RX7 74/4885TP53 4823/4885PTGES 679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.