Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRB2 | P62993 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.49 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.49 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.49 |
| ▸ | ALPI | P09923 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | XIAP | P98170 | 1/20 | 0.49 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.48 |
| ▸ | TPH1 | P17752 | 6/20 | 0.48 |
| ▸ | DPP4 | P27487 | 1/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL353300 | 0.93 | SLC7A5 (0.56) | MKNK1MKNK2SLC7A5CYP2A6ALPI | |
| SCHEMBL21690091 | 0.93 | SLC7A5 (0.56) | MKNK1MKNK2SLC7A5CYP2A6ALPI | |
| SCHEMBL7606896 | 0.93 | SLC7A5 (0.56) | MKNK1MKNK2SLC7A5CYP2A6ALPI | |
| Trifluoroacetic Acid SCHEMBL6161399 | 0.86 | SLC7A5 (0.66) | GRB2PTPN1SLC7A5ALPIPKM | |
| SCHEMBL1676744 | 0.83 | MKNK1 (0.45) | MKNK1MKNK2CYP2A6NR3C2DPP4 | |
| Hydrochloric Acid SCHEMBL31407496 | 0.81 | MKNK1 (0.45) | MKNK1MKNK2CYP2A6NR3C2DPP4 | |
| SCHEMBL31369586 | 0.80 | GRIA2 (0.66) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL31370046 | 0.79 | CYP11B1 (0.52) | SLC7A5CYP2A6ALPIPKMPTGS1 | |
| Trifluoroacetic Acid SCHEMBL3341612 | 0.79 | GRB2 (0.62) | GRB2PTPN1SLC7A5ALPIPKM | |
| SCHEMBL93495 | 0.79 | SLC7A5 (0.78) | GRB2PTPN1SLC7A5ALPIPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110098477-A1 | Method Of Producing Compound Having Anti-Hcv Activity | CHUGAI SEIYAKU KABUSHIKI KAISHA | 2011-04-28 | — | — | US | disclosed |
| EP-1908846-A1 | METHOD OF PRODUCING COMPOUND HAVING ANTI-HCV ACTION | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2008-04-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110098477-A1 | Method Of Producing Compound Having Anti-Hcv Activity | ERG28, HCCS, BCAT2 | GRB2 2186/4885PTPN1 2457/4885MKNK1 2163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.