SCHEMBL353300

SCHEMBL353300

N[C@@H](Cc1ccc(-c2cccnc2)cc1)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 2/20 0.56
ALPI P09923 1/20 0.56
PKM P14618 1/20 0.56
PTGS1 P23219 1/20 0.56
XIAP P98170 1/20 0.56
MKNK1 Q9BUB5 4/20 0.55
MKNK2 Q9HBH9 4/20 0.55
CYP2A6 P11509 1/20 0.55
TPH1 P17752 4/20 0.53
HSD17B10 Q99714 1/20 0.51
TBXAS1 P24557 2/20 0.48
GRIA2 P42262 1/20 0.47
SRR Q9GZT4 1/20 0.47
PSAT1 Q9Y617 1/20 0.47
CYP1A2 P05177 1/20 0.47
LMNA P02545 1/20 0.46
PIM1 P11309 1/20 0.46
PIM2 Q9P1W9 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7606896 1.00 SLC7A5 (0.56) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL21690091 1.00 SLC7A5 (0.56) SLC7A5ALPIPKMPTGS1XIAP
Trifluoroacetic Acid SCHEMBL1676739 0.93 GRB2 (0.53) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL31369586 0.86 GRIA2 (0.66) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL31370046 0.85 CYP11B1 (0.52) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL93495 0.84 SLC7A5 (0.78) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL180272 0.84 SLC7A5 (0.78) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL414363 0.84 SLC7A5 (0.78) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL93494 0.84 SLC7A5 (0.78) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL1796036 0.84 SLC7A5 (0.78) SLC7A5ALPIPKMPTGS1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230257343-A1 NOVEL AMINO ACID DERIVATIVES PEPTIDREAM INC (JP) 2023-08-17 US claimed
US-20070287670-A1 HUMAN GLUCAGON-LIKE PEPTIDE-1 MIMICS AND THEIR USE IN THE TREATMENT OF DIABETES AND RELATED CONDITIONS BRISTOL-MYERS SQUIBB COMPANY 2007-12-13 US claimed
EP-1572892-A4 HUMAN GLUCAGON-LIKE-PEPTIDE-1 MIMICS AND THEIR USE IN THE TREATMENT OF DIABETES AND RELATED CONDITIONS BRISTOL MYERS SQUIBB CO (US) 2007-08-22 EP claimed
EP-1615653-A2 HUMAN GLUCAGON-LIKE-PEPTIDE-1 MIMICS AND THEIR USE IN THE TREATMENT OF DIABETES AND RELATED CONDITIONS Bristol-Myers Squibb Company (US) 2006-01-18 EP claimed
EP-1572892-A2 HUMAN GLUCAGON-LIKE-PEPTIDE-1 MIMICS AND THEIR USE IN THE TREATMENT OF DIABETES AND RELATED CONDITIONS Bristol-Myers Squibb Company (US) 2005-09-14 EP claimed
CN-1630709-A Human glucagon-like-peptide-1 mimics and their use in the treatment of diabetes and related conditions BRISTOL MYERS SQUIBB CO (US) 2005-06-22 CN claimed
WO-2004094461-A2 HUMAN GLUCAGON-LIKE-PEPTIDE-1 MIMICS AND THEIR USE IN THE TREATMENT OF DIABETES AND RELATED CONDITIONS BRISTOL-MYERS SQUIBB COMPANY (US) 2004-11-04 WO claimed
US-20040127423-A1 Human glucagon-like-peptide-1 mimics and their use in the treatment of diabetes and related conditions BRISTOL-MYERS SQUIBB COMPANY 2004-07-01 US claimed
US-20030195157-A1 Human glucagon-like-peptide-1 mimics and their use in the treatment of diabetes and related conditions BRISTOL-MYERS SQUIBB COMPANY 2003-10-16 US claimed
WO-2003033671-A2 HUMAN GLUCAGON-LIKE-PEPTIDE-1 MIMICS AND THEIR USE IN THE TREATMENT OF DIABETES AND RELATED CONDITIONS BRISTOL-MYERS SQUIBB COMPANY (US) 2003-04-24 WO claimed
US-20250361274-A1 PEPTIDE AND PEPTIDE-CONTAINING AGENT PEPTIDREAM INC. (JP) 2025-11-27 US disclosed
EP-4541805-A1 PEPTIDE AND PEPTIDE-CONTAINING AGENT PeptiDream Inc. (JP) 2025-04-23 EP disclosed
WO-2023243120-A1 PEPTIDE AND PEPTIDE-CONTAINING AGENT ペプチドリーム株式会社 2023-12-21 WO disclosed
US-20230257343-A1 NOVEL AMINO ACID DERIVATIVES PEPTIDREAM INC (JP) 2023-08-17 US disclosed
US-20230257343-A1 NOVEL AMINO ACID DERIVATIVES PEPTIDREAM INC (JP) 2023-08-17 US disclosed
US-6448408-B1 CHEMICAL INTERMEDIATES IN PREPARATION OF N-MERCAPTOACYL DERIVATIVE OF PHENYLALANINE WITH PHARMALOGICAL ACTIVITY ZAMBON GROUP S.P.A. (IT) 2002-09-10 US disclosed
US-20020028946-A1 PROCESS FOR THE PREPARATION OF HETEROARYL-PHENYLALANINES ZAMBON GROUP S.P.A. (IT) 2002-03-07 US disclosed
EP-0948492-B1 PROCESS FOR THE PREPARATION OF HETEROARYL-PHENYLALANINES ZAMBON SPA (IT) 2001-07-11 EP disclosed
EP-0948492-A1 PROCESS FOR THE PREPARATION OF HETEROARYL-PHENYLALANINES ZAMBON GROUP S.p.A. (IT) 1999-10-13 EP disclosed
WO-1998028284-A1 PROCESS FOR THE PREPARATION OF HETEROARYL-PHENYLALANINES ZAMBON GROUP S.P.A. (IT) 1998-07-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070287670-A1 HUMAN GLUCAGON-LIKE PEPTIDE-1 MIMICS AND THEIR USE IN THE TREATMENT OF DIABETES AND RELATED CONDITIONS GLP1R, IAPP, GIPR SLC7A5 3843/4885ALPI 251/4885PKM 2110/4885
US-20030195157-A1 Human glucagon-like-peptide-1 mimics and their use in the treatment of diabetes and related conditions GLP1R, IAPP, GIPR SLC7A5 3672/4885ALPI 242/4885PKM 2080/4885
US-20040127423-A1 Human glucagon-like-peptide-1 mimics and their use in the treatment of diabetes and related conditions GLP1R, IAPP, GIPR SLC7A5 3672/4885ALPI 242/4885PKM 2080/4885
US-20250361274-A1 PEPTIDE AND PEPTIDE-CONTAINING AGENT BMP4, BMP1, BMPR2 SLC7A5 2541/4885ALPI 2915/4885PKM 4179/4885
US-20230257343-A1 NOVEL AMINO ACID DERIVATIVES DNPEP, BCAT1, ANPEP SLC7A5 21/4885ALPI 3748/4885PKM 3544/4885
US-20020028946-A1 PROCESS FOR THE PREPARATION OF HETEROARYL-PHENYLALANINES PAH, TYR, CYP2S1 SLC7A5 51/4885ALPI 3466/4885PKM 176/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.