Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 11/20 | 0.64 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2421306 | 0.87 | MALT1 (0.70) | MALT1TRPV1KMT2A | |
| SCHEMBL2425939 | 0.85 | MALT1 (0.64) | MALT1TRPV1KMT2A | |
| SCHEMBL10324446 | 0.81 | MALT1 (0.59) | MALT1TRPV1TRPA1 | |
| SCHEMBL16648570 | 0.81 | MAPT (0.64) | MALT1TRPV1KMT2A | |
| SCHEMBL13930766 | 0.81 | TRPA1 (0.62) | TRPV1TRPA1 | |
| Ammonia Solution, Strong SCHEMBL8128563 | 0.80 | KMT2A (0.58) | MALT1TRPV1KMT2A | |
| SCHEMBL12639914 | 0.80 | ALDH1A1 (0.72) | MALT1 | |
| SCHEMBL5220685 | 0.79 | MALT1 (0.64) | MALT1TRPV1KMT2A | |
| SCHEMBL13714900 | 0.79 | MALT1 (1.00) | MALT1TRPV1 | |
| SCHEMBL931726 | 0.78 | MALT1 (0.56) | MALT1TRPV1KMT2ATRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9150575-B2 | Piperidinylpyrazolopyridine derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2015-10-06 | — | — | US | disclosed |
| US-20150152102-A1 | PIPERIDINYLPYRAZOLOPYRIDINE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2015-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150152102-A1 | PIPERIDINYLPYRAZOLOPYRIDINE DERIVATIVE | LCAT, LPL, LCLAT1 | MALT1 4756/4885TRPV1 591/4885KMT2A 1626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.