SCHEMBL16648570

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3594750	0.89	MAPT (0.59)	MAPTCYP2C19MALT1ALDH1A1KMT2A
	SCHEMBL3435703	0.86	MAPT (0.57)	MAPTCYP2C19MALT1ALDH1A1KMT2A
	SCHEMBL2425939	0.86	MALT1 (0.64)	MALT1KMT2AMEN1TRPV1KDM4E
	SCHEMBL4865937	0.84	RORC (0.55)	MAPTCYP2C19MALT1ALDH1A1KMT2A
	SCHEMBL14338319	0.84	CYP2C19 (0.48)	MAPTCYP2C19MALT1ALDH1A1KMT2A
	SCHEMBL1253240	0.83	ALDH1A1 (0.59)	MAPTCYP2C19MALT1ALDH1A1CTSB
	SCHEMBL4255322	0.82	CTSB (0.68)	MAPTCYP2C19ALDH1A1KMT2ACTSB
	SCHEMBL3436721	0.82	ALOX15 (0.58)	MAPTCYP2C19ALDH1A1KMT2APOLB
	SCHEMBL16769731	0.81	MALT1 (0.64)	MALT1KMT2ATRPV1
	SCHEMBL195417	0.81	KDM4E (0.60)	MAPTCYP2C19ALDH1A1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.