SCHEMBL16769837

SCHEMBL16769837

CCC(C)C(=O)OCCOC(=O)C(F)(F)CC(F)(F)CC(=O)C12CC3CC(CC(C3)C1)C2

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.34
ALDH1A1 P00352 4/20 0.33
TSHR P16473 1/20 0.33
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
HSP90AA1 P07900 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16769836 0.84 LMNA (0.35) LMNAALDH1A1TSHRCYP3A4CYP2D6
SCHEMBL13556145 0.82 CYP17A1 (0.33) LMNAALDH1A1
SCHEMBL13556139 0.81 PRKCA (0.38) LMNAALDH1A1
SCHEMBL13556142 0.81 CYP17A1 (0.33) ALDH1A1
SCHEMBL13556141 0.77 CYP19A1 (0.33) ALDH1A1TSHR
SCHEMBL13556144 0.77 PRKCA (0.36) LMNAALDH1A1
SCHEMBL13556132 0.75
SCHEMBL16547493 0.75 CYP17A1 (0.34) LMNAALDH1A1
SCHEMBL13556133 0.75 MMP8 (0.34)
SCHEMBL16682462 0.74 ALDH1A1 (0.47) LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9726974-B2 Resin, photoresist composition, and method for producing photoresist pattern SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-08-08 US disclosed
US-20150153644-A1 RESIN, PHOTORESIST COMPOSITION, AND METHOD FOR PRODUCING PHOTORESIST PATTERN SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-06-04 US disclosed