Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.58 |
| ▸ | BAD | Q92934 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | RXRA | P19793 | 6/20 | 0.52 |
| ▸ | RXRB | P28702 | 5/20 | 0.52 |
| ▸ | RXRG | P48443 | 2/20 | 0.52 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.52 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | CA3 | P07451 | 1/20 | 0.48 |
| ▸ | TYR | P14679 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16749651 | 0.93 | TSHR (0.67) | HPGDTP53TSHRCA12CA1 | |
| SCHEMBL10476977 | 0.86 | TSHR (0.59) | HPGDTP53TSHRCA12CA1 | |
| SCHEMBL2197326 | 0.86 | TSHR (0.59) | HPGDTP53TSHRCA12CA1 | |
| SCHEMBL2637326 | 0.84 | TSHR (0.80) | BCL2L1BADTP53TSHRRXRA | |
| SCHEMBL14018385 | 0.84 | TSHR (0.80) | BCL2L1BADTP53TSHRRXRA | |
| Terephthalic Acid SCHEMBL9577834 | 0.84 | TSHR (0.80) | BCL2L1BADTP53TSHRRXRA | |
| SCHEMBL69873 | 0.84 | TSHR (0.80) | BCL2L1BADTP53TSHRRXRA | |
| Fluoride SCHEMBL20513068 | 0.82 | TSHR (0.75) | BCL2L1BADTP53TSHRRXRA | |
| SCHEMBL21808797 | 0.82 | TSHR (0.75) | BCL2L1BADTP53TSHRRXRA | |
| Water SCHEMBL22788424 | 0.82 | TSHR (0.75) | BCL2L1BADTP53TSHRRXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9724668-B2 | Iron metal organic framework materials | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2017-08-08 | — | — | US | disclosed |
| US-20160346759-A1 | Iron Metal Organic Framework Materials | U.S. DEPARTMENT OF ENERGY | 2016-12-01 | — | — | US | disclosed |
| US-20150152123-A1 | Aluminum Metal Organic Framework Materials | U.S. DEPARTMENT OF ENERGY | 2015-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160346759-A1 | Iron Metal Organic Framework Materials | TFRC, FTH1, FECH | BCL2L1 2235/4885BAD 4379/4885HPGD 3743/4885 |
| US-20150152123-A1 | Aluminum Metal Organic Framework Materials | AS3MT, ORAI2, ORAI3 | BCL2L1 1892/4885BAD 3491/4885HPGD 4338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.