SCHEMBL1677366

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1256138	0.85	ADORA2A (0.51)	RORBPOLBKMT2AALDH1A1MEN1
	SCHEMBL1255464	0.85	MEN1 (0.50)	RORBRORCPOLBKMT2AALDH1A1
	SCHEMBL1256222	0.82	RORB (0.60)	RORBRORCPOLBKMT2AALDH1A1
	SCHEMBL1256797	0.82	MEN1 (0.47)	RORBRORCPOLBKMT2AALDH1A1
	SCHEMBL1256268	0.82	ADORA2A (0.57)	RORBRORCPOLBKMT2AALDH1A1
	SCHEMBL1256076	0.82	ADORA2A (0.69)	POLBKMT2AALDH1A1MEN1MAPT
	SCHEMBL257608	0.81	RORB (0.83)	RORBRORCPOLBALDH1A1MAPT
	SCHEMBL257203	0.81	RORB (0.67)	RORBRORCPOLBALDH1A1TP53
	SCHEMBL1677549	0.81	L3MBTL1 (0.56)	POLBKMT2AALDH1A1MEN1MAPT
	SCHEMBL1255530	0.80	MEN1 (0.47)	RORBPOLBKMT2AALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.