Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.54 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.53 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22246858 | 0.88 | LMNA (0.74) | LMNAADORA3ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL20485265 | 0.83 | ELOVL1 (0.72) | ALDH1A1MAPTTRPA1ELOVL1MEN1 | |
| SCHEMBL28121166 | 0.82 | MAPT (0.47) | LMNAADORA3ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL20249946 | 0.80 | ELOVL1 (0.75) | ALDH1A1ELOVL1 | |
| SCHEMBL10417190 | 0.79 | ALDH1A1 (0.55) | LMNAALDH1A1MAPTTRPA1ELOVL1 | |
| SCHEMBL10274601 | 0.79 | KDM1A (0.51) | LMNAALDH1A1MAPTSMN1; SMN2TRPA1 | |
| SCHEMBL45338 | 0.79 | KDM1A (0.51) | LMNAALDH1A1MAPTSMN1; SMN2TRPA1 | |
| SCHEMBL20485374 | 0.78 | ELOVL1 (0.72) | ALDH1A1MAPTTRPA1ELOVL1MEN1 | |
| SCHEMBL20249949 | 0.78 | ELOVL1 (0.74) | LMNAALDH1A1MAPTTRPA1ELOVL1 | |
| SCHEMBL46581 | 0.78 | F10 (0.43) | LMNAADORA3ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150164904-A1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX, INC. | 2015-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150164904-A1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | SLC10A2, SLC34A2, SLC34A1 | LMNA 3035/4885ADORA3 257/4885ALDH1A1 2974/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.