Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 4/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | DDAH1 | O94760 | 3/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | GSR | P00390 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Norvaline SCHEMBL166373 | 0.94 | SLC1A2 (0.41) | NOS1SLC1A2SLC1A1GRIK1GRIK2 | |
| Norvaline SCHEMBL166375 | 0.82 | SLC1A2 (0.47) | NOS1SLC1A2SLC1A1GRIK1GRIK2 | |
| SCHEMBL169591 | 0.82 | CA12 (0.42) | NOD1CA12CA1CA2CA4 | |
| SCHEMBL168158 | 0.82 | CA12 (0.42) | NOD1CA12CA1CA2CA4 | |
| Norvaline SCHEMBL167818 | 0.80 | SLC1A2 (0.49) | NOS1SLC1A2SLC1A1GRIK1GRIK2 | |
| SCHEMBL456815 | 0.79 | NOS1 (0.45) | NOS1SLC1A2SLC1A1GRIK1GRIK2 | |
| Valine SCHEMBL167937 | 0.79 | SLC7A5 (0.47) | NOS1SLC1A2SLC1A1SLC1A3CA12 | |
| Norvaline SCHEMBL2513626 | 0.77 | SLC1A2 (0.52) | NOS1SLC1A2SLC1A1GRIK1GRIK2 | |
| Norvaline SCHEMBL2512779 | 0.77 | SLC1A2 (0.52) | NOS1SLC1A2SLC1A1GRIK1GRIK2 | |
| Norvaline SCHEMBL2513624 | 0.77 | SLC1A2 (0.52) | NOS1SLC1A2SLC1A1GRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011041870-A1 | NON-STEROIDAL ANTI-INFLAMMATORY DRUGS COADMINISTERED WITH NITRIC OXIDE AMINO ACID ESTER COMPOUNDS AS PROPHYLAXIS IN HYPERTENSIVE PATIENTS | NITROGENIX INC. (VG) | 2011-04-14 | — | — | WO | claimed |
| US-20170105959-A1 | COMPOSITIONS CONTAINING NITRIC OXIDE AMINO ACID ESTERS AND METHODS FOR IMPROVING SEXUAL PERFORMANCE | SMARTEK INTERNATIONAL, INC. | 2017-04-20 | — | — | US | disclosed |
| WO-2012027827-A1 | NITRIC OXIDE AMINO ACID ESTERS FOR SKIN REJUVENATION | ORAL DELIVERY TECHNOLOGY LTD. (CA) | 2012-03-08 | — | — | WO | disclosed |
| WO-2011041870-A1 | NON-STEROIDAL ANTI-INFLAMMATORY DRUGS COADMINISTERED WITH NITRIC OXIDE AMINO ACID ESTER COMPOUNDS AS PROPHYLAXIS IN HYPERTENSIVE PATIENTS | NITROGENIX INC. (VG) | 2011-04-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170105959-A1 | COMPOSITIONS CONTAINING NITRIC OXIDE AMINO ACID ESTERS AND METHODS FOR IMPROVING SEXUAL PERFORMANCE | NOS1, NOS2, NOS3 | NOS1 1/4885SLC1A2 80/4885SLC1A1 99/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.