Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.46 |
| ▸ | PLK4 | O00444 | 6/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.40 |
| ▸ | MAT2A | P31153 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16783120 | 0.91 | RXFP1 (0.54) | RXFP1PLK4NTRK1SMN1; SMN2RAB9A | |
| SCHEMBL16783143 | 0.89 | RXFP1 (0.47) | RXFP1PLK4NTRK1SMN1; SMN2MAPT | |
| SCHEMBL16783112 | 0.87 | RXFP1 (0.48) | RXFP1SMN1; SMN2MAPTOPRM1OPRD1 | |
| SCHEMBL23633377 | 0.87 | TP53 (0.50) | RXFP1MAPTOPRM1OPRD1KDM4E | |
| SCHEMBL16783131 | 0.85 | RXFP1 (0.54) | RXFP1SMN1; SMN2RAB9AMAPTOPRM1 | |
| SCHEMBL16783126 | 0.84 | RXFP1 (0.55) | RXFP1SMN1; SMN2MAPTOPRM1OPRD1 | |
| SCHEMBL23633382 | 0.81 | KDM4E (0.45) | RXFP1SMN1; SMN2RAB9AMAPTKDM4E | |
| SCHEMBL23633375 | 0.81 | MAT2A (0.49) | RXFP1SMN1; SMN2RAB9AMAPTOPRM1 | |
| SCHEMBL23633374 | 0.81 | OPRM1 (0.48) | RXFP1NTRK1MAPTOPRM1OPRD1 | |
| SCHEMBL24334609 | 0.79 | KDM4E (0.53) | RXFP1SMN1; SMN2RAB9AMAPTOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150164910-A1 | ANTIVIRAL COMPOUNDS AND METHODS OF USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2015-06-18 | — | — | US | disclosed |
| US-20150164910-A1 | ANTIVIRAL COMPOUNDS AND METHODS OF USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2015-06-18 | — | — | US | disclosed |
| US-20150164910-A1 | ANTIVIRAL COMPOUNDS AND METHODS OF USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2015-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150164910-A1 | ANTIVIRAL COMPOUNDS AND METHODS OF USE | EIF2AK2, RNASE1, HAVCR2 | RXFP1 4611/4885PLK4 2027/4885NTRK1 4444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.