Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | MAT2A | P31153 | 3/20 | 0.47 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23633377 | 0.88 | TP53 (0.50) | OPRM1OPRD1MAT2APSMD14L3MBTL1 | |
| SCHEMBL16783111 | 0.86 | L3MBTL1 (0.49) | OPRM1OPRD1MAT2APSMD14L3MBTL1 | |
| SCHEMBL23633375 | 0.86 | MAT2A (0.49) | OPRM1OPRD1MAT2APSMD14L3MBTL1 | |
| SCHEMBL16783126 | 0.85 | RXFP1 (0.55) | OPRM1OPRD1MAT2APSMD14L3MBTL1 | |
| SCHEMBL16783145 | 0.85 | OPRM1 (0.51) | OPRM1OPRD1MAT2APSMD14L3MBTL1 | |
| SCHEMBL16783112 | 0.84 | RXFP1 (0.48) | OPRM1OPRD1MAT2APSMD14L3MBTL1 | |
| SCHEMBL16783194 | 0.84 | ALDH1A1 (0.55) | OPRM1OPRD1MAT2APSMD14L3MBTL1 | |
| SCHEMBL24334609 | 0.83 | KDM4E (0.53) | OPRM1OPRD1MAT2APSMD14L3MBTL1 | |
| SCHEMBL29944917 | 0.83 | KDM4E (0.53) | OPRM1OPRD1MAT2APSMD14L3MBTL1 | |
| SCHEMBL23633379 | 0.83 | ALDH1A1 (0.65) | OPRM1OPRD1MAT2APSMD14L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11059817-B2 | Potent antiviral pyrazolopyridine compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11059817-B2 | Potent antiviral pyrazolopyridine compounds | MAVS, VRK1, VRK2 | OPRM1 2324/4885OPRD1 1052/4885MAT2A 4620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.