Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR3 | O60755 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.33 |
| ▸ | MERTK | Q12866 | 1/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16229795 | 0.92 | GALR3 (0.35) | GALR3PLA2G1BPKMATG4BHTT | |
| SCHEMBL16229759 | 0.90 | RORC (0.33) | CARM1PRMT6 | |
| SCHEMBL16784638 | 0.89 | LMNA (0.34) | SLC6A9 | |
| SCHEMBL16229784 | 0.89 | DPP4 (0.34) | PKMSLC6A9 | |
| SCHEMBL16784637 | 0.88 | GALR3 (0.43) | GALR3PLA2G1BPKMATG4BHTT | |
| SCHEMBL16784643 | 0.88 | GALR3 (0.43) | GALR3PLA2G1BPKMATG4BHTT | |
| SCHEMBL16229812 | 0.86 | SLC6A9 (0.39) | GALR3PLA2G1BPKMATG4BCARM1 | |
| SCHEMBL16229771 | 0.83 | GALR3 (0.38) | GALR3CARM1PRMT6SLC6A9 | |
| SCHEMBL16229772 | 0.83 | AXL (0.37) | GALR3SLC6A9AXLTYRO3MERTK | |
| SCHEMBL16229803 | 0.83 | SLC6A9 (0.48) | GALR3SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9051280-B2 | Tetraline and indane derivatives, pharmaceutical compositions containing them, and their use in therapy | AbbVie Deutschland GmbH & Co. KG (DE) | 2015-06-09 | — | — | US | disclosed |