SCHEMBL16790773

SCHEMBL16790773

N#Cc1cccc(N2C(=C3N(c4cccc(C#N)c4)C4CCCCC4N3c3cccc(C#N)c3)N(c3cccc(C#N)c3)C3CCCCC32)c1

nearest known ligand 0.49

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 6/20 0.49
DRD3 P35462 5/20 0.49
NOTUM Q6P988 2/20 0.46
ALOX5 P09917 1/20 0.44
NSD2 O96028 1/20 0.43
FADS1 O60427 1/20 0.41
HRH3 Q9Y5N1 1/20 0.40
KMT2A Q03164 1/20 0.40
MCOLN3 Q8TDD5 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16790795 0.79 MAOA (0.44) HRH3
SCHEMBL6496695 0.73 DRD2 (0.49) DRD2DRD3NOTUMALOX5NSD2
SCHEMBL16789240 0.72 HRH3 (0.49) HRH3
SCHEMBL18088237 0.72 FADS1 (0.39) DRD2DRD3NOTUMALOX5NSD2
SCHEMBL16789226 0.72 SLC18A3 (0.43) KMT2A
SCHEMBL29809089 0.72 DRD2 (0.74) DRD2DRD3NOTUMALOX5NSD2
SCHEMBL3537217 0.72 DRD2 (0.74) DRD2DRD3NOTUMALOX5NSD2
SCHEMBL16789934 0.72 DRD2 (0.59) DRD2DRD3NOTUMALOX5NSD2
SCHEMBL16480396 0.71 FADS1 (0.48) DRD2DRD3NOTUMALOX5NSD2
SCHEMBL15800697 0.71 DRD2 (0.79) DRD2DRD3NOTUMALOX5NSD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10541260-B2 Organic photoelectric conversion element, optical area sensor, imaging device, and imaging apparatus CANON KABUSHIKI KAISHA (JP) 2020-01-21 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed
US-9846385-B2 Organic light emitting element and display device CANON KABUSHIKI KAISHA (JP) 2017-12-19 US disclosed
US-20150162549-A1 ORGANIC LIGHT EMITTING ELEMENT AND DISPLAY DEVICE CANON KABUSHIKI KAISHA (JP) 2015-06-11 US disclosed