Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16794891 | 0.83 | NTRK1 (0.41) | NTRK1ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL16794850 | 0.82 | NTRK1 (0.38) | NTRK1ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL16794856 | 0.75 | LMNA (0.37) | NTRK1ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL16814655 | 0.73 | ALDH1A1 (0.44) | NTRK1ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL16794889 | 0.68 | NTRK1 (0.40) | NTRK1ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL29469528 | 0.68 | NTRK1 (0.58) | NTRK1ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL1002968 | 0.68 | NTRK1 (0.58) | NTRK1ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL25327891 | 0.66 | HPGD (0.55) | NTRK1ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL16794875 | 0.66 | NTRK1 (0.37) | NTRK1ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL20696083 | 0.64 | MEN1 (0.54) | NTRK1ALDH1A1MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015088564-A1 | P2X4 RECEPTOR MODULATING COMPOUNDS | SUNOVION PHARMACEUTICALS INC. (US) | 2015-06-18 | — | — | WO | disclosed |
| WO-2015088564-A1 | P2X4 RECEPTOR MODULATING COMPOUNDS | SUNOVION PHARMACEUTICALS INC. (US) | 2015-06-18 | — | — | WO | disclosed |