Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16814655 | 0.87 | ALDH1A1 (0.44) | NTRK1ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL16794891 | 0.83 | NTRK1 (0.41) | NTRK1ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL16794889 | 0.80 | NTRK1 (0.40) | NTRK1ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL16794896 | 0.76 | NPSR1 (0.38) | ALDH1A1KDM4ENPSR1ADORA3RAB9A | |
| SCHEMBL14397606 | 0.72 | ALDH1A1 (0.51) | NTRK1ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL16794922 | 0.72 | MMP2 (0.36) | NTRK1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL16794967 | 0.71 | NTRK1 (0.48) | NTRK1ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL16794866 | 0.71 | NOD2 (0.40) | NTRK1MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL16794840 | 0.66 | NTRK1 (0.43) | NTRK1ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL14397205 | 0.66 | ALDH1A1 (0.42) | NTRK1ALDH1A1KDM4EHPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015088564-A1 | P2X4 RECEPTOR MODULATING COMPOUNDS | SUNOVION PHARMACEUTICALS INC. (US) | 2015-06-18 | — | — | WO | disclosed |
| WO-2015088564-A1 | P2X4 RECEPTOR MODULATING COMPOUNDS | SUNOVION PHARMACEUTICALS INC. (US) | 2015-06-18 | — | — | WO | disclosed |