Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GALR2 | O43603 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16794891 | 0.90 | NTRK1 (0.41) | LMNAGLAL3MBTL1NTRK1SMN1; SMN2 | |
| SCHEMBL16814655 | 0.81 | ALDH1A1 (0.44) | LMNAGLAELANEL3MBTL1NTRK1 | |
| SCHEMBL16794889 | 0.75 | NTRK1 (0.40) | L3MBTL1NTRK1KMT2AALDH1A1MEN1 | |
| SCHEMBL16794840 | 0.75 | NTRK1 (0.43) | LMNAGLAELANEL3MBTL1NTRK1 | |
| SCHEMBL16794922 | 0.74 | MMP2 (0.36) | LMNANTRK1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL16794875 | 0.73 | NTRK1 (0.37) | ELANEL3MBTL1NTRK1SMN1; SMN2KDM4E | |
| SCHEMBL16794967 | 0.72 | NTRK1 (0.48) | LMNAGLAL3MBTL1NTRK1SMN1; SMN2 | |
| SCHEMBL16794832 | 0.70 | GABRP (0.39) | LMNAGLAL3MBTL1GSK3BKDM4E | |
| SCHEMBL16794921 | 0.68 | LMNA (0.37) | LMNAL3MBTL1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL16794835 | 0.68 | CSF1R (0.50) | LMNAL3MBTL1SMN1; SMN2KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015088564-A1 | P2X4 RECEPTOR MODULATING COMPOUNDS | SUNOVION PHARMACEUTICALS INC. (US) | 2015-06-18 | — | — | WO | disclosed |