Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | MAT2A | P31153 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16794922 | 0.89 | MMP2 (0.36) | NTRK1ALDH1A1HPGDCYP2C19MEN1 | |
| SCHEMBL16795024 | 0.87 | CSF1R (0.35) | CSF1RNTRK1ALDH1A1HPGDCYP1A2 | |
| SCHEMBL16814655 | 0.81 | ALDH1A1 (0.44) | CSF1RNTRK1ALDH1A1HPGDCYP1A2 | |
| SCHEMBL16794891 | 0.79 | NTRK1 (0.41) | CSF1RNTRK1ALDH1A1HPGDCYP1A2 | |
| SCHEMBL16794889 | 0.76 | NTRK1 (0.40) | NTRK1ALDH1A1MEN1KMT2A | |
| SCHEMBL16794835 | 0.74 | CSF1R (0.50) | CSF1RALDH1A1HPGDCYP1A2CYP2C19 | |
| SCHEMBL16794875 | 0.74 | NTRK1 (0.37) | CSF1RNTRK1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL16795011 | 0.71 | CHEK1 (0.44) | CSF1RALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL16794921 | 0.70 | LMNA (0.37) | CSF1RALDH1A1HPGDCYP1A2CYP2C19 | |
| SCHEMBL16794967 | 0.69 | NTRK1 (0.48) | NTRK1ALDH1A1HPGDHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015088564-A1 | P2X4 RECEPTOR MODULATING COMPOUNDS | SUNOVION PHARMACEUTICALS INC. (US) | 2015-06-18 | — | — | WO | disclosed |
| WO-2015088564-A1 | P2X4 RECEPTOR MODULATING COMPOUNDS | SUNOVION PHARMACEUTICALS INC. (US) | 2015-06-18 | — | — | WO | disclosed |