Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ESRRA | P11474 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16796720 | 0.86 | MEN1 (0.43) | ALDH1A1HSD17B10CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL16796718 | 0.84 | ALDH1A1 (0.46) | ALDH1A1HSD17B10CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL2117439 | 0.82 | KMT2A (0.55) | ALDH1A1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL2457012 | 0.81 | KMT2A (0.64) | ALDH1A1NPSR1MEN1KMT2AL3MBTL1 | |
| SCHEMBL2114760 | 0.76 | L3MBTL1 (0.54) | ALDH1A1MEN1KMT2AL3MBTL1POLB | |
| SCHEMBL6283431 | 0.75 | L3MBTL1 (0.53) | ALDH1A1HSD17B10MEN1KMT2AL3MBTL1 | |
| SCHEMBL2544694 | 0.74 | L3MBTL1 (0.52) | ALDH1A1NPSR1MEN1KMT2AL3MBTL1 | |
| SCHEMBL15902156 | 0.72 | ALDH1A1 (0.67) | ALDH1A1MEN1KMT2AL3MBTL1POLB | |
| SCHEMBL8560375 | 0.72 | L3MBTL1 (0.67) | ALDH1A1NPSR1MEN1KMT2AL3MBTL1 | |
| SCHEMBL9164757 | 0.71 | L3MBTL1 (0.60) | ALDH1A1HSD17B10MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015088564-A1 | P2X4 RECEPTOR MODULATING COMPOUNDS | SUNOVION PHARMACEUTICALS INC. (US) | 2015-06-18 | — | — | WO | disclosed |