Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | GPR183 | P32249 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 2/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.45 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.44 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.44 |
| ▸ | COMT | P21964 | 1/20 | 0.43 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2931146 | 0.88 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2AKDM4ETSHR | |
| SCHEMBL23111584 | 0.82 | FAAH (0.55) | ALDH1A1MEN1KMT2AKDM4ETSHR | |
| SCHEMBL15094206 | 0.81 | MGLL (0.65) | ALDH1A1MEN1KMT2ASMN1; SMN2SIGMAR1 | |
| SCHEMBL15094162 | 0.81 | MGLL (0.62) | ALDH1A1KDM4ESMN1; SMN2SIGMAR1FAAH | |
| SCHEMBL20137138 | 0.80 | VEGFA (0.61) | ALDH1A1MEN1KMT2AKDM4ETSHR | |
| SCHEMBL2930265 | 0.80 | LMNA (0.48) | ALDH1A1MEN1KMT2AKDM4ETSHR | |
| SCHEMBL20503399 | 0.79 | MGLL (0.50) | MEN1KMT2ASIGMAR1FAAHMGLL | |
| SCHEMBL3088484 | 0.78 | MPO (0.73) | ALDH1A1MEN1KMT2AKDM4EALOX15 | |
| SCHEMBL21802543 | 0.78 | MGLL (0.54) | ALDH1A1MEN1KMT2AKDM4ETSHR | |
| SCHEMBL2931705 | 0.78 | AKR1C3 (0.65) | ALDH1A1MEN1KMT2AKDM4ESIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015086693-A1 | PYRAZOLOPYRIMIDIN-2-YL DERIVATIVES AS JAK INHIBITORS | ALMIRALL, S.A. (ES) | 2015-06-18 | — | — | WO | disclosed |