Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3416907 | 0.82 | HRH3 (0.47) | ALDH1A1LIPGMEN1KMT2A | |
| SCHEMBL16795211 | 0.81 | POLB (0.46) | ROCK1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL3045151 | 0.80 | LIPG (0.47) | FAAHALDH1A1LIPGMEN1KMT2A | |
| SCHEMBL17136271 | 0.77 | DGAT1 (0.42) | ROCK1FAAHALDH1A1KDM4E | |
| SCHEMBL15094169 | 0.76 | ROCK1 (0.51) | ROCK1ALDH1A1KDM4EMGLL | |
| SCHEMBL16795444 | 0.74 | GRIN2B (0.38) | GRIN2BKDM4E | |
| SCHEMBL25207195 | 0.74 | ROCK1 (0.54) | ROCK1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL18579955 | 0.73 | ROCK1 (0.53) | ROCK1ALDH1A1LIPGMPOKDM4E | |
| SCHEMBL16795231 | 0.73 | ALDH1A1 (0.50) | FAAHALDH1A1MEN1KMT2AMPO | |
| SCHEMBL23111584 | 0.73 | FAAH (0.55) | FAAHALDH1A1MEN1KMT2AMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015086693-A1 | PYRAZOLOPYRIMIDIN-2-YL DERIVATIVES AS JAK INHIBITORS | ALMIRALL, S.A. (ES) | 2015-06-18 | — | — | WO | disclosed |