Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 2/20 | 0.56 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.56 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.56 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.44 |
| ▸ | IDH1 | O75874 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.39 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HNF4A | P41235 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14146996 | 0.82 | PRSS1 (0.61) | PRSS1PRSS2PRSS3CALM1IDH1 | |
| SCHEMBL8665442 | 0.79 | PRSS1 (0.61) | PRSS1PRSS2PRSS3CALM1IDH1 | |
| SCHEMBL16795534 | 0.78 | HDAC8 (0.60) | — | |
| SCHEMBL16795551 | 0.78 | F10 (0.61) | — | |
| SCHEMBL93850 | 0.77 | MAOA (0.54) | — | |
| SCHEMBL16795802 | 0.77 | KMO (0.52) | PRSS1PRSS2PRSS3 | |
| SCHEMBL7782873 | 0.76 | PRSS1 (0.54) | PRSS1PRSS2PRSS3CALM1IDH1 | |
| SCHEMBL1926951 | 0.75 | FOLH1 (0.66) | PRSS1PRSS2PRSS3CA1CA2 | |
| SCHEMBL7613502 | 0.72 | CALM1 (0.75) | PRSS1PRSS2PRSS3CALM1IDH1 | |
| SCHEMBL13971231 | 0.72 | CALM1 (0.75) | PRSS1PRSS2PRSS3CALM1IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015087094-A1 | NEW ARYLALKENYLPROPARGYLAMINE DERIVATIVES EXHIBITING NEUROPROTECTIVE ACTION FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | SEMMELWEIS EGYETEM (HU) | 2015-06-18 | — | — | WO | disclosed |