Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 5/20 | 0.55 |
| ▸ | CES2 | O00748 | 5/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | DAO | P14920 | 1/20 | 0.55 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA4 | P22748 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrogen Sulfide SCHEMBL28111724 | 0.97 | CES1 (0.52) | CES1CES2TSHRALDH1A1DAO | |
| Hydrochloric Acid SCHEMBL28496848 | 0.97 | CES1 (0.52) | CES1CES2TSHRALDH1A1DAO | |
| Water SCHEMBL27612226 | 0.97 | CES1 (0.52) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL312084 | 0.89 | CES1 (0.50) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL11623306 | 0.88 | CES1 (0.48) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL8494639 | 0.85 | CA2 (0.48) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL11742945 | 0.85 | CES1 (0.46) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL5031044 | 0.85 | KMT2A (0.47) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL11621561 | 0.83 | HPGD (0.48) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL31543778 | 0.82 | AKT1 (0.52) | CES1CES2TSHRALDH1A1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 660 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119899356-A | Self-healing polyurethane elastomer material based on dynamic reversible covalent bonds, preparation method and seamless telescopic structure based on material | 南京兴佑交通科技有限公司 | 2025-04-29 | — | — | CN | claimed |
| US-12264174-B2 | Process for preparing imetelstat | GERON CORPORATION (US) | 2025-04-01 | — | — | US | claimed |
| CN-115417954-B | Photo-thermal dual-curing polyurethane polymer, preparation method and composite material thereof | 万华化学（北京）有限公司 | 2025-04-01 | — | — | CN | claimed |
| CN-119144144-B | High-elasticity waterproof skin-feel tablecloth based on flexible polymer and preparation method thereof | 星远控股有限公司 | 2025-03-25 | — | — | CN | claimed |
| US-20240262854-A1 | Process for Preparing Imetelstat | BIOPHARMA CREDIT PLC, AS COLLATERAL AGENT (GB) | 2024-08-08 | — | — | US | claimed |
| CN-110891961-B | Improved process for the preparation of imaelstat | 美国杰龙生物医药公司 | 2023-06-30 | — | — | CN | claimed |
| US-20220404084-A1 | METHODS, SYSTEMS, DEVICES, AND FORMULATIONS FOR CRYOGENIC FLUIDS | GLACIA, INC. (US) | 2022-12-22 | — | — | US | claimed |
| WO-2022261569-A2 | METHODS, SYSTEMS, DEVICES, AND FORMULATIONS FOR CRYOGENIC FLUIDS | GLACIA, INC. (US) | 2022-12-15 | — | — | WO | claimed |
| CN-115417954-A | Photo-thermal dual-curable polyurethane polymer, preparation method and composite material thereof | 万华化学（北京）有限公司 | 2022-12-02 | — | — | CN | claimed |
| US-11332489-B2 | Process for preparing imetelstat | GERON CORPORATION (US) | 2022-05-17 | — | — | US | claimed |
| WO-1997030733-A1 | MAGNETIC RESONANCE BLOOD POOL AGENTS BOUND TO HUMAN SERUM ALBUMIN | MALLINCKRODT MEDICAL, INC. (US) | 1997-08-28 | — | — | WO | claimed |
| WO-1997030734-A1 | MAGNETIC RESONANCE BLOOD POOL AGENTS | MALLINCKRODT MEDICAL, INC. (US) | 1997-08-28 | — | — | WO | claimed |
| EP-0782632-A1 | A METHOD FOR IDENTIFYING AND USING COMPOUNDS THAT INACTIVATE HIV-1 AND OTHER RETROVIRUSES BY ATTACKING HIGHLY CONSERVED ZINC FINGERS IN THE VIRAL NUCLEOCAPSID PROTEIN | THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by the Secretary of the Department of Health and Human Services (US) | 1997-07-09 | — | — | EP | claimed |
| WO-1996009406-A9 | A METHOD FOR IDENTIFYING AND USING COMPOUNDS THAT INACTIVATE HIV-1 AND OTHER RETROVIRUSES BY ATTACKING HIGHLY CONSERVED ZINC FINGERS IN THE VIRAL NUCLEOCAPSID PROTEIN | — | 1996-05-23 | — | — | WO | claimed |
| WO-1996009406-A1 | A METHOD FOR IDENTIFYING AND USING COMPOUNDS THAT INACTIVATE HIV-1 AND OTHER RETROVIRUSES BY ATTACKING HIGHLY CONSERVED ZINC FINGERS IN THE VIRAL NUCLEOCAPSID PROTEIN | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1996-03-28 | — | — | WO | claimed |
| US-4412072-A | STABILIZED WITH A PEROXIDE, SULFUR, POLYSULFIDE, METAL SULFIDE OR A HALOGEN | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1983-10-25 | — | — | US | claimed |
| US-4167415-A | Photocurable composition comprising copolymer of maleic acid monoester and α-olefin compound | KANSAI PAINT CO., LTD. (JP) | 1979-09-11 | — | — | US | claimed |
| US-4092172-A | Photocurable composition comprising a copolymer of a maleic acid monoester with an α-olefine | KANSAI PAINT CO., LTD. (JA) | 1978-05-30 | — | — | US | claimed |
| US-4046727-A | Thermosettable acrylic resin composition for powder coating | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-09-06 | — | — | US | claimed |
| US-3954584-A | Photopolymerizable vinylurethane liquid composition | KANSAI PAINT COMPANY (JA) | 1976-05-04 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11332489-B2 | Process for preparing imetelstat | RNGTT, TERT, TRMT1L | CES1 2345/4885CES2 3546/4885TSHR 2083/4885 |
| US-20240262854-A1 | Process for Preparing Imetelstat | TERT, RNGTT, TRMT1L | CES1 2380/4885CES2 3750/4885TSHR 1886/4885 |
| US-12264174-B2 | Process for preparing imetelstat | TERT, RNGTT, TRMT1L | CES1 2380/4885CES2 3750/4885TSHR 1886/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.