SCHEMBL1680282

SCHEMBL1680282

C=CCOC(=O)C(C)(C)N

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.40
TSHR P16473 2/20 0.40
CACNA1B Q00975 1/20 0.40
APBA1 Q02410 1/20 0.40
CYP3A4 P08684 1/20 0.38
ALDH1A1 P00352 3/20 0.37
HSD17B10 Q99714 2/20 0.37
TDP1 Q9NUW8 1/20 0.37
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
KDM4E B2RXH2 2/20 0.33
TP53 P04637 1/20 0.33
HPGD P15428 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.32
RHOA P61586 1/20 0.32
LMNA P02545 1/20 0.31
GAA P10253 1/20 0.31
MAPK1 P28482 1/20 0.31
POLB P06746 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL10920602 0.98 MAPT (0.39) MAPTTSHRCACNA1BAPBA1CYP3A4
SCHEMBL10454577 0.85 MAPT (0.39) MAPTTSHRCACNA1BAPBA1CYP3A4
Glycinebetaine SCHEMBL940799 0.83 BBOX1 (0.34) MAPTTSHRCACNA1BAPBA1
SCHEMBL25689533 0.83 MAPT (0.38) MAPTTSHRCACNA1BAPBA1CYP3A4
SCHEMBL19906417 0.83 MAPT (0.38) MAPTTSHRCACNA1BAPBA1CYP3A4
SCHEMBL27348374 0.82 TDP1 (0.34) MAPTTSHRCACNA1BAPBA1TDP1
SCHEMBL194466 0.82 TSHR (0.42) MAPTTSHRCACNA1BAPBA1CYP3A4
SCHEMBL7866089 0.82 TSHR (0.42) MAPTTSHRCACNA1BAPBA1CYP3A4
SCHEMBL1680215 0.80 TSHR (0.40) MAPTTSHRCACNA1BAPBA1CYP3A4
SCHEMBL6194635 0.80 TSHR (0.41) MAPTTSHRCACNA1BAPBA1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024137394-A1 CLEANSING COMPOSITIONS AND METHODS FOR THE SAME COLGATE-PALMOLIVE COMPANY (US) 2024-06-27 WO claimed
US-20240189203-A1 Liquid Personal Care Compositions and Methods for the Same COLGATE-PALMOLIVE COMPANY (US) 2024-06-13 US claimed
EP-4199896-A1 LIQUID PERSONAL CARE COMPOSITIONS AND METHODS FOR THE SAME Colgate-Palmolive Company (US) 2023-06-28 EP claimed
US-20230055665-A1 DELIVERY CARRIER INTO CELL ITO, KABUSIKIKAISYA (JP) 2023-02-23 US claimed
US-20140141978-A1 WATER MISCIBLE MICROEMULSIONS OF WATER INSOLUBLE FILM FORMING POLYMERS ISP Investmentts Inc. (US) 2014-05-22 US claimed
US-8452221-B2 Fixation fluid, fixation method, image forming method, fixation device, and image forming apparatus RICOH COMPANY, LTD. (JP) 2013-05-28 US claimed
WO-2013009734-A2 WATER MISCIBLE MICROEMULSIONS OF WATER INSOLUBLE FILM FORMING POLYMERS ISP INVESTMENTS INC. (US) 2013-01-17 WO claimed
US-20110229231-A1 FIXATION FLUID, FIXATION METHOD, IMAGE FORMING METHOD, FIXATION DEVICE, AND IMAGE FORMING APPARATUS RICOH COMPANY, LTD. (JP) 2011-09-22 US claimed
EP-2350744-A1 FIXATION FLUID, FIXATION METHOD, IMAGE FORMING METHOD, FIXATION DEVICE, AND IMAGE FORMING APPARATUS Ricoh Company, Ltd. (JP) 2011-08-03 EP claimed
WO-2010058668-A1 FIXATION FLUID, FIXATION METHOD, IMAGE FORMING METHOD, FIXATION DEVICE, AND IMAGE FORMING APPARATUS RICOH COMPANY, LTD. (JP) 2010-05-27 WO claimed
CN-1597825-A Adhesive for dry laminate and composite plastic film laminated with the adhesive KANJI HAYASHI (JP) 2005-03-23 CN claimed
US-20050014892-A1 Antistatic adhesive for water-based or solvent-based dry laminate and complex plastic film HAYASHI KANJI (JP) 2005-01-20 US claimed
EP-1498440-A2 Antistatic adhesive for plastic film Hayashi, Kanji (JP) 2005-01-19 EP claimed
EP-1072311-B1 Heat resistant catalyst sheet and process for producing same SUMITOMO CHEMICAL CO (JP) 2004-09-22 EP claimed
US-6465389-B1 COMBINING AN ARAMID FIBER AND A CATALYST COMPONENT-CONTAINING TITANIA FIBER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-10-15 US claimed
EP-1072311-A2 Heat resistant catalyst sheet and process for producing same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-01-31 EP claimed
EP-1072312-A2 Acid resistant catalyst sheet and process for producing same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-01-31 EP claimed
JP-1299205-A None JP disclosed
US-5538549-A COLOR AND SOLVENT MIXTURE SUCH AS WATER AND PIGMENT PARTICLES BROTHER KOGYO KABUSHIKI KAISHA (JP) 1996-07-23 US disclosed
JP-H01299205-A LIQUID HERBICIDE HOECHST AG 1989-12-04 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140141978-A1 WATER MISCIBLE MICROEMULSIONS OF WATER INSOLUBLE FILM FORMING POLYMERS MYB, ERG28, POLR1C MAPT 116/4885TSHR 4634/4885CACNA1B 4650/4885
US-20230055665-A1 DELIVERY CARRIER INTO CELL CTSA, ATG4A, ATG7 MAPT 1714/4885TSHR 4448/4885CACNA1B 3318/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.