Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CASP2 | P42575 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18180992 | 0.84 | TSHR (0.44) | TSHRMEN1KMT2APOLBFAAH | |
| SCHEMBL9322077 | 0.82 | TSHR (0.40) | TSHRMEN1KMT2APOLBFAAH | |
| SCHEMBL22174072 | 0.78 | TSHR (0.52) | TSHRMEN1KMT2APOLBFAAH | |
| SCHEMBL19273990 | 0.77 | TSHR (0.39) | TSHRMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL135382 | 0.77 | ALDH1A1 (0.35) | TSHRPOLBKDM4EMAPK1HIF1A | |
| SCHEMBL10136017 | 0.77 | CASP2 (0.47) | MEN1KMT2AFAAHCASP2EPHX1 | |
| SCHEMBL18164189 | 0.77 | TSHR (0.55) | TSHRMEN1KMT2APOLBFAAH | |
| SCHEMBL16477882 | 0.77 | MEN1 (0.61) | TSHRMEN1KMT2A | |
| SCHEMBL16422261 | 0.77 | TSHR (0.41) | TSHRMEN1KMT2APOLBFAAH | |
| SCHEMBL960689 | 0.76 | KDM4E (0.56) | TSHRKDM4EMAPK1HIF1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9329479-B2 | Lithographic printing plate precusor | AGFA GRAPHICS NV (BE) | 2016-05-03 | — | — | US | disclosed |
| US-20150168837-A1 | LITHOGRAPHIC PRINTING PLATE PRECUSOR | ECO3 BV (BE) | 2015-06-18 | — | — | US | disclosed |