SCHEMBL1680427

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1680773	0.81	AR (0.47)	KMT2ASLC22A12ALDH1A1MAPTHTR1A
	SCHEMBL921472	0.81	AR (0.47)	MEN1KMT2ASLC22A12ALDH1A1MAPT
	SCHEMBL1106848	0.77	TSHR (0.41)	MEN1KMT2AALDH1A1MAPTL3MBTL1
	SCHEMBL510507	0.75	GAA (0.43)	MEN1KMT2ASLC22A12ALDH1A1MAPT
	SCHEMBL18603934	0.74	POLB (0.53)	MEN1KMT2ASLC22A12ALDH1A1MAPT
	SCHEMBL30872202	0.74	POLB (0.53)	MEN1KMT2ASLC22A12ALDH1A1MAPT
	SCHEMBL12352101	0.71	MRGPRX1 (0.36)	MEN1KMT2AALDH1A1L3MBTL1MRGPRX1
	SCHEMBL1680741	0.71	CYP2E1 (0.40)	MEN1KMT2AALDH1A1L3MBTL1MRGPRX1
	SCHEMBL1680332	0.70	VEGFA (0.38)	SLC22A12ALDH1A1MAPTMRGPRX1HTR1A
	SCHEMBL2389927	0.70	HTR1A (0.55)	MEN1KMT2AALDH1A1L3MBTL1MRGPRX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.