SCHEMBL1680773

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1680427	0.81	MEN1 (0.38)	ARLMNASLC22A12KMT2AALDH1A1
	SCHEMBL921472	0.80	AR (0.47)	ARLMNASMN1; SMN2SLC22A12KMT2A
	SCHEMBL12808365	0.76	MAPT (0.39)	ARLMNASMN1; SMN2ADRB2KMT2A
	SCHEMBL1106848	0.75	TSHR (0.41)	LMNASMN1; SMN2KMT2AALDH1A1HTT
	SCHEMBL1680440	0.72	AR (0.43)	ARLMNASMN1; SMN2ADRB2KMT2A
	SCHEMBL1680719	0.71	AR (0.49)	ARLMNASLC22A12FNTAFNTB
	SCHEMBL510507	0.70	GAA (0.43)	SMN1; SMN2SLC22A12KMT2AALDH1A1HPGD
	SCHEMBL12352098	0.70	HPGD (0.36)	ARLMNASMN1; SMN2ADRB2KMT2A
	SCHEMBL1680855	0.70	DPP4 (0.42)	LMNASMN1; SMN2ALDH1A1HTTHPGD
	SCHEMBL1436765	0.69	HPGD (0.59)	LMNASMN1; SMN2KMT2AALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.