SCHEMBL1680440

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL510507	0.84	GAA (0.43)	ALDH1A1HPGDMEN1KMT2AKDM4E
	SCHEMBL509367	0.82	AR (0.43)	ARALDH1A1HPGDMEN1KMT2A
	SCHEMBL5957247	0.82	POLB (0.45)	ARALDH1A1HPGDMEN1KMT2A
	SCHEMBL1106848	0.81	TSHR (0.41)	MAOAALDH1A1HPGDMEN1KMT2A
	SCHEMBL4964133	0.79	ALDH1A1 (0.41)	ALDH1A1HPGDKMT2AKDM4EL3MBTL1
	SCHEMBL1680773	0.72	AR (0.47)	ARALDH1A1HPGDKMT2AMAPT
	SCHEMBL1680332	0.71	VEGFA (0.38)	ALDH1A1HPGDKDM4EMAPTFNTA
	SCHEMBL1680588	0.70	AR (0.49)	ARALDH1A1MEN1KMT2AL3MBTL1
	SCHEMBL5957174	0.69	—	—
	SCHEMBL2259191	0.69	MAOB (0.57)	ARMAOAMAOBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.