SCHEMBL16804491

SCHEMBL16804491

CCCN(C)C(=O)C(C)(C)F

nearest known ligand 0.34

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MLYCD O95822 1/20 0.34
CTSK P43235 3/20 0.33
CA12 O43570 2/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
PDK2 Q15119 1/20 0.33
RIPK1 Q13546 6/20 0.33
FAAH O00519 5/20 0.31
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.31
CA1 P00915 1/20 0.31
CA7 P43166 1/20 0.31
CA14 Q9ULX7 1/20 0.31
CES1 P23141 3/20 0.30
CES2 O00748 1/20 0.30
MEN1 O00255 1/20 0.30
CYP1A2 P05177 1/20 0.30
KMT2A Q03164 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8366044 0.84 CTSK (0.41) MLYCDCTSKCA12CA2CA9
SCHEMBL9010937 0.81 RIPK1 (0.37) CA12CA2CA9RIPK1TSHR
SCHEMBL12741115 0.79 CA12 (0.34) CTSKCA12CA2CA9RIPK1
SCHEMBL21896014 0.77 RIPK1 (0.50) RIPK1
SCHEMBL25467799 0.77 MLYCD (0.33) MLYCDCA12CA2CA9PDK2
SCHEMBL12452607 0.76 FAAH (0.39) CTSKCA12CA9PDK2FAAH
SCHEMBL4570201 0.74 THRB (0.42) MLYCDPDK2
SCHEMBL20018677 0.72 CA12 (0.32) CA12CA2CA9RIPK1CA1
SCHEMBL18760966 0.72 RIPK1 (0.35) CA12CA2CA9RIPK1
SCHEMBL16508865 0.71 FAAH (0.43) CTSKCA12CA9FAAHCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3731329-A1 ELECTROLYTE, ELECTROCHEMICAL DEVICE, LITHIUM ION SECONDARY BATTERY, AND MODULE DAIKIN INDUSTRIES, LTD. (JP) 2020-10-28 EP disclosed
WO-2015087151-A1 NOVEL AZAINDOLE DERIVATIVES AS SELECTIVE HISTONE DEACETYLASE (HDAC) INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME CHONG KUN DANG PHARMACEUTICAL CORP. (KR) 2015-06-18 WO disclosed