SCHEMBL1680585

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1680711	0.81	MAOB (0.47)	MAOBMAOATDP1L3MBTL1CYP3A4
	SCHEMBL922635	0.81	CYP2E1 (0.48)	MAOACYP3A4
	SCHEMBL4161373	0.79	ENPP2 (0.41)	MAOACYP3A4
	SCHEMBL4150602	0.78	SPHK2 (0.51)	MAOBCYP4F2CYP4A11NR4A2SPHK2
	SCHEMBL1680567	0.77	MAOB (0.49)	MAOBCYP4F2CYP4A11BCHEMAOA
	SCHEMBL28237963	0.77	MAOB (0.72)	MAOBCYP4F2CYP4A11BCHEMAOA
	SCHEMBL16886110	0.76	MAOB (0.70)	MAOBCYP4F2CYP4A11BCHEMAOA
	SCHEMBL1680329	0.76	MAOB (0.39)	MAOBCYP3A4
	SCHEMBL1680519	0.76	MAOB (0.39)	MAOBTDP1CYP3A4
	SCHEMBL1680718	0.76	PNMT (0.41)	MAOBCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.