SCHEMBL1680519

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1680718	0.81	PNMT (0.41)	MAOBCYP3A4CYP2C9CYP2C19CYP2E1
	SCHEMBL920993	0.81	ALDH1A1 (0.46)	CYP3A4CYP2C9CYP2C19CYP2E1CYP2A6
	SCHEMBL1680329	0.81	MAOB (0.39)	MAOBCYP3A4CYP2C9CYP2C19CYP2E1
	SCHEMBL4161373	0.81	ENPP2 (0.41)	CYP3A4CYP2C9CYP2C19CYP2E1CYP2A6
	SCHEMBL922635	0.80	CYP2E1 (0.48)	CYP3A4CYP2C9CYP2C19CYP2E1CYP2A6
	SCHEMBL4155001	0.78	PDE4A (0.40)	CYP3A4CYP2C9CYP2C19CYP2E1CYP2A6
	SCHEMBL12908105	0.78	LMNA (0.44)	MAOBCYP2C9CYP2C19ALDH1A1CYP1A2
	Hydrochloric Acid SCHEMBL921294	0.77	MAOB (0.44)	MAOBALDH1A1ICAM1SELETAAR1
	SCHEMBL1680585	0.76	MAOB (0.50)	MAOBCYP3A4TDP1
	SCHEMBL4155387	0.73	ICAM1 (0.54)	CYP3A4CYP2C9CYP2C19ALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.