SCHEMBL1680761

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1680417	0.79	CYP2A6 (0.53)	LOXL2ALOX5TAAR1SMN1; SMN2MAOA
	SCHEMBL1680878	0.78	TAAR1 (0.50)	LOXL2TAAR1MAOBIDO1AGXT
	SCHEMBL5476883	0.76	IDO1 (0.41)	LOXL2ALOX5TAAR1EPHX2TP53
	SCHEMBL8304377	0.76	ALOX5 (0.43)	LOXL2ALOX5TAAR1EPHX2TP53
	SCHEMBL16148795	0.76	ALOX5 (0.41)	LOXL2ALOX5EPHX2TP53SMN1; SMN2
	SCHEMBL14829415	0.73	LOXL2 (0.84)	LOXL2TAAR1MAOBIDO1AGXT
	SCHEMBL1680352	0.73	ALOX5 (0.42)	ALOX5EPHX2TP53SMN1; SMN2MAPT
	SCHEMBL13696940	0.72	ALOX5 (0.63)	ALOX5EPHX2
	SCHEMBL28812876	0.72	MEN1 (0.39)	LOXL2TP53SMN1; SMN2MAPTMAOA
	SCHEMBL21063	0.70	—	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.