Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1680761 | 0.72 | LOXL2 (0.52) | CYP2E1CYP3A4CYP2A6CYP2C9CYP2B6 | |
| SCHEMBL8322277 | 0.69 | L3MBTL1 (0.69) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL10206263 | 0.69 | PRMT6 (0.59) | CYP2E1CYP3A4CYP2A6CYP2C9CYP2B6 | |
| SCHEMBL10055033 | 0.68 | LMNA (0.61) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL6419238 | 0.68 | LMNA (0.61) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL3005414 | 0.68 | TAAR1 (0.46) | LOXL2MAPTALDH1A1GAAL3MBTL1 | |
| SCHEMBL2064760 | 0.66 | MAPT (0.57) | MEN1KMT2AMAPTALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL3027696 | 0.66 | TAAR1 (0.44) | LOXL2MAPTALDH1A1KCNH3MAOA | |
| SCHEMBL416817 | 0.65 | APP (0.47) | MEN1KMT2ALOXL2MAPTALDH1A1 | |
| SCHEMBL352533 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103980264-A | Aminopyridines antifungal compound, preparation method and application thereof | UNIV PLA 2ND MILITARY MEDICAL | 2014-08-13 | — | — | CN | disclosed |