Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.45 |
| ▸ | F12 | P00748 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CLK1 | P49759 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15149335 | 0.85 | MIF (0.48) | NQO2MIFMAPTELANE | |
| SCHEMBL3911487 | 0.83 | NQO2 (0.47) | NQO2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL16808231 | 0.79 | GABRB1 (0.40) | GABRB1GABRB2NPC1RAB9AMAPT | |
| SCHEMBL16808314 | 0.78 | ESR1 (0.41) | MEN1NPC1RAB9AKMT2ACYP2C9 | |
| SCHEMBL23458554 | 0.77 | KMT2A (0.49) | NQO2F12MEN1NPC1RAB9A | |
| SCHEMBL4560058 | 0.76 | HSD17B1 (0.44) | NQO2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL617014 | 0.76 | MAPT (0.52) | GABRB1GABRB2KMT2AEPHX2MAPT | |
| SCHEMBL32687527 | 0.75 | RAB9A (0.49) | MEN1NPC1RAB9AKMT2AMAPT | |
| SCHEMBL7438712 | 0.75 | ADRB2 (0.40) | MEN1KMT2AEPHX2PLAUMAPT | |
| SCHEMBL616504 | 0.75 | CA1 (0.46) | MEN1RAB9AKMT2AGAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015087857-A1 | ARYL AMIDINE COMPOUND AND BACTERICIDAL AGENT | 日本曹達株式会社 | 2015-06-18 | — | — | WO | disclosed |