Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | CLK1 | P49759 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | F12 | P00748 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8390404 | 0.91 | GABRA1 (0.50) | NPC1RAB9AGABRA1GABRG2GABRB3 | |
| SCHEMBL29912865 | 0.84 | KDM4E (0.56) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL6370340 | 0.84 | KDM4E (0.56) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL1415273 | 0.84 | CES2 (0.55) | KMT2AMEN1NPC1RAB9AGABRA1 | |
| SCHEMBL25736545 | 0.83 | GABRA1 (0.44) | NPC1RAB9AGABRA1GABRG2GABRB3 | |
| SCHEMBL539749 | 0.83 | CES2 (0.48) | KMT2AMEN1NPC1RAB9AGABRA1 | |
| SCHEMBL3526930 | 0.81 | PLAU (0.45) | KMT2AMEN1RAB9AF12GABRA1 | |
| SCHEMBL38810 | 0.81 | CA12 (0.59) | KMT2AMEN1NPC1RAB9AESR1 | |
| SCHEMBL30371904 | 0.80 | CA1 (0.64) | KMT2AMEN1NPC1RAB9ACLK1 | |
| SCHEMBL363156 | 0.80 | CA1 (0.64) | KMT2AMEN1NPC1RAB9ACLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230046947-A1 | REACTIVE CONJUGATES | DEBIOPHARM RESEARCH & MANUFACTURING S.A. (CH) | 2023-02-16 | — | — | US | disclosed |
| US-20230046947-A1 | REACTIVE CONJUGATES | DEBIOPHARM RESEARCH & MANUFACTURING S.A. (CH) | 2023-02-16 | — | — | US | disclosed |
| CN-115279416-A | Reactive conjugates | 德彪药业国际股份公司 | 2022-11-01 | — | — | CN | disclosed |
| EP-4069311-A1 | REACTIVE CONJUGATES | Debiopharm Research & Manufacturing SA (CH) | 2022-10-12 | — | — | EP | disclosed |
| WO-2021110860-A1 | REACTIVE CONJUGATES | DEBIOPHARM RESEARCH & MANUFACTURING S.A. (CH) | 2021-06-10 | — | — | WO | disclosed |
| WO-2021110860-A1 | REACTIVE CONJUGATES | DEBIOPHARM RESEARCH & MANUFACTURING S.A. (CH) | 2021-06-10 | — | — | WO | disclosed |
| CN-104768914-A | Method for producing 6,6'-(ethylenedioxy)di-2-naphthoic acid diester | TEIJIN LTD | 2015-07-08 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230046947-A1 | REACTIVE CONJUGATES | FCGR3B, FCGR1A, FCGR2A | KMT2A 1155/4885MEN1 221/4885NPC1 1378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.