SCHEMBL1680865

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1681046	0.94	GALR3 (0.39)	LMNASMN1; SMN2EGLN1GALR3NR2F2
	SCHEMBL1680924	0.91	SMN1; SMN2 (0.50)	LMNASMN1; SMN2EGLN1HPGDFAAH
	SCHEMBL921221	0.88	TRPV1 (0.42)	LMNASMN1; SMN2EGLN1GALR3NR2F2
	SCHEMBL920719	0.88	SMN1; SMN2 (0.47)	LMNASMN1; SMN2EGLN1HPGDFAAH
	SCHEMBL921893	0.87	TRPV1 (0.46)	LMNASMN1; SMN2GALR3NR2F2HPGD
	SCHEMBL920222	0.86	TRPV1 (0.45)	LMNASMN1; SMN2HPGDKMT2AKDM4E
	SCHEMBL921133	0.86	TSHR (0.42)	LMNASMN1; SMN2EGLN1GALR3NR2F2
	SCHEMBL920800	0.86	LMNA (0.40)	LMNASMN1; SMN2EGLN1HPGDKMT2A
	SCHEMBL1680395	0.85	GALR3 (0.38)	LMNASMN1; SMN2EGLN1GALR3NR2F2
	SCHEMBL921603	0.85	TRPV1 (0.42)	LMNASMN1; SMN2EGLN1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.