SCHEMBL1680867

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1680887	0.93	EGLN1 (0.56)	EGLN1MAPK14CYP3A4MMP13FFAR1
	SCHEMBL13491424	0.92	CYP3A4 (0.61)	EGLN1MAPK14CYP3A4MMP13MAPT
	SCHEMBL1681262	0.92	FFAR1 (0.57)	EGLN1MAPK14CYP3A4MMP13FFAR1
	SCHEMBL13491676	0.90	MMP13 (0.64)	EGLN1MAPK14CYP3A4MMP13FFAR1
	SCHEMBL1681075	0.90	MMP13 (0.61)	CYP3A4MMP13MAPTLMNARAB9A
	SCHEMBL13491593	0.90	EGLN1 (0.55)	EGLN1MAPK14CYP3A4MMP13MAPT
	SCHEMBL1681116	0.89	ALOX15 (0.58)	EGLN1MAPK14CYP3A4MMP13FFAR1
	SCHEMBL13491471	0.89	EGLN1 (0.54)	EGLN1CYP3A4MMP13MAPTLMNA
	SCHEMBL13491480	0.88	EGLN1 (0.51)	EGLN1MAPK14CYP3A4MMP13FFAR1
	SCHEMBL13491492	0.87	MMP13 (0.53)	EGLN1CYP3A4MMP13FFAR1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.